The tools in this project provide the ability to create de novo assemblies from SOLiD colorspace reads, thus facilitating the characterization of genomic sequences for which no closely related reference genome exists. The short-read assembler at the core of this pipeline is Velvet, developed by Daniel Zerbino and Ewan Birney at the European Bioinformatics Institute. The tools in this package, together with Velvet, can be used to assemble high-coverage SOLiD reads from microbial genomes into nucleotide sequence contigs of several thousand bases, and scaffolds of tens of thousands of bases.
The tools in this project provide the ability to create de novo assemblies from SOLiD colorspace reads, thus facilitating the characterization of genomic sequences for which no closely related reference genome exists. The short-read assembler at the core of this pipeline is Velvet, developed by Daniel Zerbino and Ewan Birney at the European Bioinformatics Institute. The tools in this package, together with Velvet, can be used to assemble high-coverage SOLiD reads from microbial genomes into nucleotide sequence contigs of several thousand bases, and scaffolds of tens of thousands of bases.