Nature Reviews Genetics 16, 376 (2015)
Technology: A drop in single-cell challenges
Darren J. Burgess.
Single-cell high-throughput RNA sequencing (scRNA-seq) approaches are providing unprecedented insights into the constituent cell types and intercellular heterogeneity underlying various tissues. However, one limitation is that the cost or labour intensiveness of current approaches for generating single-cell sequencing libraries using valve-based microfluidic chips or microplates