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Nature Reviews Microbiology 13, 426 (2015)

Broad-spectrum antivirals against viral fusion

Frederic Vigant, Nuno C. Santos, Benhur Lee.
Effective antivirals have been developed against specific viruses, such as HIV, Hepatitis C virus and influenza virus. This 'one bug–one drug' approach to antiviral drug development can be successful, but it may be inadequate for responding to an increasing diversity of viruses that cause significant