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Nature Reviews Molecular Cell Biology 16, 431 (2015)

Control of mammalian gene expression by selective mRNA export

Vihandha O. Wickramasinghe, Ronald A. Laskey.
Nuclear export of mRNAs is a crucial step in the regulation of gene expression, linking transcription in the nucleus to translation in the cytoplasm. Although important components of the mRNA export machinery are well characterized, such as transcription-export complexes TREX and TREX-2, recent work has