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Nature Reviews Molecular Cell Biology 16, 391 (2015)

DNA damage response: Damage by Helicobacter pylori

Eytan Zlotorynski.
Infection with the gastric bacterium Helicobacter pylori can cause chromosomal instability (CIN) and promote tumorigenesis. Koeppel et al. compared the DNA damage response (DDR) following H. pylori infection with that induced by other genotoxic treatments in human gastric cells and observed reduced