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Nature Reviews Molecular Cell Biology 16, 391 (2015)

Techniques: microRNA switches to isolate specific cells

Kim Baumann.
For many cell types, no specific cell-surface markers that would facilitate their isolation have been identified. In this study, Miki et al. describe a method to isolate specific cell types on the basis of their endogenous microRNA (miRNA) activity. The authors designed 'miRNA switches',