熱點文獻
PNAS
Retro-translocation of mitochondrial intermembrane space proteins [Biochemistry]
P. Bragoszewski, M. Wasilewski, P. Sakowska, A. Gornicka, L. Bottinger, J. Qiu, N. Wiedemann, A. Chacinska.
The content of mitochondrial proteome is maintained through two highly dynamic processes, the influx of newly synthesized proteins from the cytosol and the protein degradation. Mitochondrial proteins are targeted to the intermembrane space by the mitochondrial intermembrane space assembly pathway that couples their import and oxidative folding. The folding trap...