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PNAS

Alpha-actinin binding kinetics modulate cellular dynamics and force generation [Biophysics and Computational Biology]

A. J. Ehrlicher, R. Krishnan, M. Guo, C. M. Bidan, D. A. Weitz, M. R. Pollak.
The actin cytoskeleton is a key element of cell structure and movement whose properties are determined by a host of accessory proteins. Actin cross-linking proteins create a connected network from individual actin filaments, and though the mechanical effects of cross-linker binding affinity on actin networks have been investigated in reconstituted...