Nature Methods 12, 503 (2015)
Correlated light and electron microscopy: ultrastructure lights up!
Pascal de Boer, Jacob P Hoogenboom, Ben N G Giepmans.
Correlated light and electron microscopy (CLEM) gives context to biomolecules studied with fluorescence microscopy. This Review discusses recent improvements and guides readers on probes, instrumentation and sample preparation to implement CLEM.